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If a woman with an established diagnosis of recurrent vulvovaginal candidiasis does not respond to an imidazole, infection with a resistant non– C. albicans species may be present. Terconazole vaginal cream (Terazol) is the agent of choice when infection with a species other than C. albicans is suspected. The potent interference of this agent with the cytochrome P450 isoenzymes makes C. tropicalis and C. glabrata more susceptible to treatment.

After the acute episode of recurrent vulvovaginal candidiasis has been treated, subsequent prophylaxis or maintenance therapy is essential. In one clinical trial, women with a history of recurrent vulvovaginal candidiasis were randomized to receive 400 mg of ketoconazole for 14 days or clotrimazole in the form of 100-mg vaginal suppositories for seven days. 18 One week after treatment, the clinical cure rate was higher than 80 percent in both groups. Two months after treatment, in the absence of any maintenance therapy, 53 percent of women in the ketoconazole treatment group and 63 percent of those in the clotrimazole treatment group had recurrences.

Several maintenance regimens have been studied. In one clinical trial, 74 women with recurrent vulvovaginal candidiasis were treated for an acute episode with 400 mg of ketoconazole per day for 14 days. 19 The women were then randomized to receive one of three treatments: placebo, 400 mg of ketoconazole administered orally for five days after the menses for six months, or 100 mg of ketoconazole administered orally each day for six months. The six-month recurrence rates were 71 percent for the placebo group, 29 percent for the cyclic-regimen group and 5 percent for the daily-regimen group.

Maintenance therapy needs to be given frequently enough to prevent vaginal regrowth, but the optimal dosing interval is not clear. One study suggested that the weekly administration of 0.8 percent terconazole vaginal cream is nearly as effective as daily treatment with ketoconazole. DENIM Denim trousers Schmidttakahashi Cheap Sale Find Great UznBn
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A monthly 150-mg dose of orally administered fluconazole has been shown to reduce the incidence of recurrences by 50 percent. 22 Itraconazole, in a dosage of 200 mg 23 or 400 mg 24 administered orally once a month, also has been found to decrease the recurrence rate by approximately 50 percent. Boric acid, administered in a 600-mg vaginal suppository twice daily for two weeks and then daily during menstruation, has been effective in the treatment of women with resistant infection. 3 However, the use of boric acid is limited by significant local irritation and the possibility of intoxication. 25

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‌Traduire votre stratégie en plan d’action, c’est traduire une ligne directrice générale en tâches spécifiques. Cet exercice est essentiel parce qu’il vous force à vous projeter dans le détail des opérations que vous prévoyez de mettre en place.

Il vous permet notamment d’évaluer avec plus de précision l’ampleurdes efforts et des ressources (financières, humaines…) que vous devrez investir pour mener à bien votre plan.

Comme je vous l'ai dit plus tôt dans le cours, nous allons créer ce plan d'action sur un tableur. En l'occurrence, je vaisutiliser Google Sheets mais si vous préférez vous pouvez utiliser Microsoft Excel.

Les captures d'écran qui vont illustrer la version texte du cours peuvent être difficiles à lire.Pour une lecture détaillée, je vous invite à regarder le screencast qui accompagne ce cours ou à directementouvrir le tableur en question .

Avant de lister toutes vos actions, vous commencerez par renseigner chaque colonne de votre tableur.

Pour ne laisser aucune zone d’ombre, vous prendrez soin d’associer chaque action avec un certain nombre d’informations :

Une fois que la structure de votre plan d'action sera créée, vous pourrez la remplir. C'est làque le vrai travail commence et que "la magie"s'opère.Ligne par ligne, colonne après colonne, vous allez être obligé devous poser systématiquement toutes les bonnes questions.

Cela vous permettra :

Je vais maintenant vous montrer, étape par étape, comment est-ce que j'aurais rempli le tableau. Pour tirer un maximum de ce cours, je vous invite à le re-créer et à le compléter au maximum par vous même. Sivous êtes bloqué, vous pourrez toujours jetez un coup d'oeil à ma proposition.

le ou les objectifs qu’elle vise à atteindre ;

objectifs

le ou les indicateurs de suivi de sa performance ou KPI ;

indicateurs de suivi de sa performance

le nom ou le contact de la personne chargée de cette action;

Opaque structure types are used to represent named structure types that do not have a body specified. This corresponds (for example) to the C notion of a forward declared structure.

LLVM has several different basic types of constants. This section describes them all and their syntax.

Simple Constants

The one non-intuitive notation for constants is the hexadecimal form of floating-point constants. For example, the form ‘’ is equivalent to (but harder to read than) ‘’. The only time hexadecimal floating-point constants are required (and the only time that they are generated by the disassembler) is when a floating-point constant must be emitted but it cannot be represented as a decimal floating-point number in a reasonable number of digits. For example, NaN’s, infinities, and other special values are represented in their IEEE hexadecimal format so that assembly and disassembly do not cause any bits to change in the constants.

When using the hexadecimal form, constants of types half, float, and double are represented using the 16-digit form shown above (which matches the IEEE754 representation for double); half and float values must, however, be exactly representable as IEEE 754 half and single precision, respectively. Hexadecimal format is always used for long double, and there are three forms of long double. The 80-bit format used by x86 is represented as followed by 20 hexadecimal digits. The 128-bit format used by PowerPC (two adjacent doubles) is represented by followed by 32 hexadecimal digits. The IEEE 128-bit format is represented by followed by 32 hexadecimal digits. Long doubles will only work if they match the long double format on your target. The IEEE 16-bit format (half precision) is represented by followed by 4 hexadecimal digits. All hexadecimal formats are big-endian (sign bit at the left).

There are no constants of type x86_mmx.

Boolean constants Integer constants Floating-point constants Null pointer constants Token constants

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Complex constants are a (potentially recursive) combination of simple constants and smaller complex constants.

Structure constants Array constants Vector constants Zero initialization Metadata node

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are always implicitly valid (link-time) constants. These constants are explicitly referenced when the identifier for the global is used and always have pointer type. For example, the following is a legal LLVM file:

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